{"id":6478,"date":"2026-10-13T16:38:41","date_gmt":"2026-10-13T07:38:41","guid":{"rendered":"https:\/\/aclinic.jp\/column\/?p=6478"},"modified":"2026-10-13T16:42:02","modified_gmt":"2026-10-13T07:42:02","slug":"mounjaro-itsuyaseru","status":"publish","type":"post","link":"https:\/\/aclinic.jp\/column\/mounjaro-itsuyaseru\/","title":{"rendered":"\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3044\u3064\u304b\u3089\u75e9\u305b\u308b\uff1f\u52b9\u679c\u3092\u611f\u3058\u308b\u6642\u671f\u3084\u4f53\u91cd\u5909\u5316\u30fb\u52b9\u304b\u306a\u3044\u3068\u304d\u306e\u5bfe\u51e6\u6cd5\u3092\u89e3\u8aac"},"content":{"rendered":"<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u59cb\u3081\u308b\u65e5\u6570\u306f\u3001\u4eba\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u98df\u6b32\u304c\u5909\u308f\u308b\u6642\u671f\u3068\u4f53\u91cd\u304c\u6e1b\u308b\u6642\u671f\u306f\u3001\u5fc5\u305a\u3057\u3082\u4e00\u81f4\u3057\u307e\u305b\u3093\u3002<\/p>\n<div class=\"ac-caution\">\n<div class=\"ac-caution__head\">\n<div class=\"ac-caution__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-caution__title\">\u56fd\u5185\u306e\u627f\u8a8d\u9069\u5fdc\u306f2\u578b\u7cd6\u5c3f\u75c5<\/span><\/p>\n<\/div>\n<div class=\"ac-caution__body\">\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u6e1b\u91cf\u76ee\u7684\u306e\u4f7f\u7528\u306f\u3001\u56fd\u5185\u3067\u306f\u627f\u8a8d\u3055\u308c\u305f\u9069\u5fdc\u306e\u7bc4\u56f2\u5916\u3067\u3059\u3002<\/p>\n<p>\u540c\u3058\u6210\u5206\u306e\u30bc\u30c3\u30d7\u30d0\u30a6\u30f3\u30c9\u3068\u306f\u3001\u88fd\u54c1\u3054\u3068\u306e\u627f\u8a8d\u9069\u5fdc\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d4\u30fb6\u30fb17\u9805<\/a>\uff0f<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2206038\">SURMOUNT-1\u539f\u8457<\/a>\uff0f<a href=\"https:\/\/www.pmda.go.jp\/files\/000275251.pdf\">\u80a5\u6e80\u75c7\u6cbb\u7642\u85ac\u306e\u5b89\u5168\u30fb\u9069\u6b63\u4f7f\u7528\u306b\u95a2\u3059\u308b\u30b9\u30c6\u30fc\u30c8\u30e1\u30f3\u30c8<\/a>\u3002<\/small><\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u3053\u306e\u8a18\u4e8b\u3067\u308f\u304b\u308b\u3053\u3068<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec01\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u4f53\u91cd\u304c\u6e1b\u308a\u59cb\u3081\u308b\u6642\u671f<\/a><\/li>\n<li><a href=\"#sec02\">1\u30fb2\u30fb3\u30fb6\u30f6\u6708\u306e\u4f53\u91cd\u5909\u5316\u306e\u898b\u65b9<\/a><\/li>\n<li><a href=\"#sec03\">5mg\u30921\u30f6\u6708\u4f7f\u3063\u305f\u5834\u5408\u306e\u52b9\u679c<\/a><\/li>\n<li><a href=\"#sec04\">\u98df\u6b32\u3084\u4f53\u91cd\u306b\u8868\u308c\u308b\u5909\u5316<\/a><\/li>\n<li><a href=\"#sec05\">\u75e9\u305b\u306a\u3044\u7406\u7531\u3068\u4f53\u91cd\u304c\u505c\u6ede\u3057\u305f\u3068\u304d\u306e\u5bfe\u5fdc<\/a><\/li>\n<li><a href=\"#sec06\">\u7d9a\u3051\u308b\u671f\u9593\u3068\u4e2d\u6b62\u30fb\u518d\u958b\u306e\u6ce8\u610f\u70b9<\/a><\/li>\n<li><a href=\"#sec07\">\u52b9\u679c\u304c\u51fa\u308b\u6642\u671f\u306b\u3064\u3044\u3066\u306e\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li>\n<li><a href=\"#sec08\">\u4f53\u91cd\u5909\u5316\u3092\u78ba\u8a8d\u3059\u308b\u3068\u304d\u306e\u30dd\u30a4\u30f3\u30c8\u307e\u3068\u3081<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u5834\u5408\u306f\u3001\u6295\u4e0e\u65e5\u3084\u7528\u91cf\u3001\u4f53\u8abf\u306e\u8a18\u9332\u3092\u3082\u3068\u306b\u51e6\u65b9\u533b\u3078\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-pr ac-pr--v2\">\n<div class=\"ac-pr__header\"><span class=\"ac-pr__pr\">PR\u5e83\u544a<\/span><\/p>\n<div class=\"ac-pr__title\">DMM\u30aa\u30f3\u30e9\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af\u306e\u30de\u30f3\u30b8\u30e3\u30ed\u51e6\u65b9\u306f\u6708\u984d12,000\u5186(\u7a0e\u8fbc)\uff01<\/div>\n<\/div>\n<div class=\"ac-pr__body\">\n<div class=\"ac-pr__row\">\n<div class=\"ac-pr__rating\">\n<div class=\"ac-pr__rec\"><span class=\"ac-pr__rec-label\">\u304a\u3059\u3059\u3081\u5ea6<\/span><\/p>\n<div class=\"ac-pr__stars\">\u2605\u2605\u2605\u2605\u2605<\/div>\n<\/div>\n<div class=\"ac-pr__score\"><span class=\"ac-pr__score-label\">\u7dcf\u5408\u8a55\u4fa1<\/span><\/p>\n<div class=\"ac-pr__score-value\"><strong>9.5<\/strong>\/10\u70b9<\/div>\n<\/div>\n<\/div>\n<div class=\"ac-pr__banner\"><a href=\"https:\/\/aclinic.jp\/column\/jump\/dmm-m.html\" rel=\"nofollow noopener\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/aclinic.jp\/column\/wp-content\/uploads\/2026\/07\/DMM\u30aa\u30f3\u30e9\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af-\u30de\u30f3\u30b8\u30e3\u30ed-1.png\" alt=\"https:\/\/aclinic.jp\/column\/wp-content\/uploads\/2026\/07\/DMM\u30aa\u30f3\u30e9\u30a4\u30f3\u30af\u30ea\u30cb\u30c3\u30af-\u30de\u30f3\u30b8\u30e3\u30ed.png\" width=\"600\" height=\"403\" class=\"aligncenter size-full wp-image-5088\" \/><\/a><\/div>\n<\/div>\n<div class=\"ac-pr__row\">\n<div class=\"ac-pr__tables\">\n<table class=\"ac-pr__table\">\n<thead>\n<tr>\n<th>\u30de\u30f3\u30b8\u30e3\u30ed<\/th>\n<th>\u30ea\u30d9\u30eb\u30b5\u30b9<\/th>\n<th>\u8a3a\u5bdf\u6599<\/th>\n<th>\u914d\u9001\u6599<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>12,000\u5186(\u7a0e\u8fbc)(\u203b1)<\/td>\n<td>7,920\u5186(\u7a0e\u8fbc)\uff5e(\u203b2)<\/td>\n<td>\u7121\u6599(\u203b3)<\/td>\n<td>550\u5186(\u7a0e\u8fbc)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"ac-pr__table\">\n<thead>\n<tr>\n<th>\u8a3a\u7642<\/th>\n<th>\u30af\u30fc\u30dd\u30f3<\/th>\n<th>\u914d\u9001<\/th>\n<th>\u89e3\u7d04\u30fb\u8fd4\u91d1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>24\u6642\u9593<br \/>\n\u203b\u5e74\u672b\u5e74\u59cb\u9664\u304f<\/td>\n<td>\u3042\u308a<\/td>\n<td>\u6700\u77ed\u5f53\u65e5<\/td>\n<td>\u5236\u5ea6\u3042\u308a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div class=\"ac-pr__radar\" data-scores=\"9 10 10 9 9 10 10 9\" data-labels=\"\u6599\u91d1\u306e\u5b89\u3055|\u4e88\u7d04\u3057\u3084\u3059\u3055|\u7d99\u7d9a\u3057\u3084\u3059\u3055|\u5229\u7528\u6e80\u8db3\u5ea6|\u30b5\u30dd\u30fc\u30c8\u4f53\u5236|\u5229\u4fbf\u6027|\u30aa\u30f3\u30e9\u30a4\u30f3\u5bfe\u5fdc|\u5b89\u5fc3\u611f\"><\/div>\n<\/div>\n<div class=\"ac-pr__row\">\n<div class=\"ac-pr__point-wrap\">\n<div class=\"ac-pr__point-head\">\u304a\u3059\u3059\u3081\u30dd\u30a4\u30f3\u30c8<\/div>\n<div class=\"ac-pr__point-body\">\u9ad8\u30b3\u30b9\u30d1\u3067\u59cb\u3081\u3089\u308c\u308b\uff01<\/div>\n<\/div>\n<div class=\"ac-pr__cta-wrap\"><a href=\"https:\/\/aclinic.jp\/column\/jump\/dmm-m.html\" class=\"ac-pr__cta\" rel=\"nofollow noopener\" target=\"_blank\">\u7121\u6599\u8a3a\u7642\u4e88\u7d04\u306f\u3053\u3061\u3089<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: right;\"><span style=\"font-size: 12px;\">(\u203b1)\u30de\u30f3\u30b8\u30e3\u30ed2.5mg\u306e\u3089\u304f\u3089\u304f\u5b9a\u671f\u4fbf1\u30f6\u6708\u3054\u3068\u3092\u9078\u629e\u3057\u305f\u5834\u5408<br \/>(\u203b2)\u30ea\u30d9\u30eb\u30b5\u30b93mg\u30fb30\u9320\u3042\u305f\u308a\u3002\u3089\u304f\u3089\u304f\u5b9a\u671f\u4fbf6\u30f6\u6708\u3054\u3068\u306e\u6708\u3042\u305f\u308a\u306e\u85ac\u4ee3\u3067\u3059\u30026\u30f6\u6708\u5206\u306e\u85ac\u4ee3\u7dcf\u984d47,520\u5186(\u7a0e\u8fbc)\u3001\u9001\u6599\u5225\u3002<br \/>(\u203b3)\u7121\u65ad\u30ad\u30e3\u30f3\u30bb\u30eb\u306f1,000\u5186(\u7a0e\u8fbc)\u304c\u8acb\u6c42\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u95a2\u9023\u8a18\u4e8b\u306f\u3053\u3061\u3089<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"https:\/\/aclinic.jp\/column\/manjaro-onlineshinryo-osusume\/\">\u30de\u30f3\u30b8\u30e3\u30ed\u304c\u5b89\u3044\u304a\u3059\u3059\u3081\u30aa\u30f3\u30e9\u30a4\u30f3\u8a3a\u7642\u30af\u30ea\u30cb\u30c3\u30af\uff01\u6599\u91d1\u76f8\u5834\u3084\u5373\u65e5\u767a\u9001\u5bfe\u5fdc\u306e\u6709\u7121\u30fb\u5f8c\u6094\u3057\u306a\u3044\u9078\u3073\u65b9\u307e\u3067\u89e3\u8aac<\/a><\/li>\n<li><a href=\"https:\/\/aclinic.jp\/column\/medeikarudaietto-yasui-ol\/\">\u30e1\u30c7\u30a3\u30ab\u30eb\u30c0\u30a4\u30a8\u30c3\u30c8\u304c\u5b89\u3044\u304a\u3059\u3059\u3081\u30aa\u30f3\u30e9\u30a4\u30f3\u8a3a\u7642\u30af\u30ea\u30cb\u30c3\u30af9\u9078\uff01\u5b89\u304f\u7d99\u7d9a\u3059\u308b\u65b9\u6cd5\u30fb\u6599\u91d1\u76f8\u5834\u30fb\u5931\u6557\u3057\u306a\u3044\u9078\u3073\u65b9\u307e\u3067\u89e3\u8aac\u30102026\u5e7410\u6708\u6700\u65b0\u3011<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h2 id=\"sec01\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3044\u3064\u304b\u3089\u75e9\u305b\u308b\u52b9\u679c\u304c\u51fa\u308b\uff1f<\/h2>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u59cb\u3081\u3066\u4f55\u65e5\u3067\u4f53\u91cd\u304c\u6e1b\u308b\u304b\u306f\u3001\u4e00\u5f8b\u306b\u306f\u7b54\u3048\u3089\u308c\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u98df\u6b32\u304c\u5909\u308f\u3063\u3066\u3082\u3001\u3059\u3050\u306b\u4f53\u91cd\u304c\u6e1b\u308b\u3068\u306f\u9650\u3089\u306a\u3044\u305f\u3081\u3067\u3059\u3002<\/p>\n<p>\u300c\u9593\u98df\u304c\u6e1b\u3063\u305f\u300d\u300c\u5c11\u91cf\u3067\u6e80\u8179\u306b\u306a\u308b\u300d\u3068\u3044\u3063\u305f\u611f\u899a\u3068\u3001\u4f53\u91cd\u8a08\u306e\u6570\u5024\u306f\u5225\u3005\u306b\u8a18\u9332\u3059\u308b\u3068\u3001\u8a3a\u5bdf\u3067\u5909\u5316\u3092\u4f1d\u3048\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3044\u3064\u304b\u3089\u75e9\u305b\u308b\u52b9\u679c\u304c\u51fa\u308b\uff1f<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec01-01\">\u98df\u6b32\u304c\u5909\u308f\u3063\u3066\u3082\u4f53\u91cd\u304c\u6e1b\u308b\u6642\u671f\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b<\/a><\/li>\n<li><a href=\"#sec01-02\">\u6295\u4e0e\u958b\u59cb\u304b\u30891\u9031\u9593\u3067\u4f53\u91cd\u304c\u6e1b\u308b\u3068\u306f\u9650\u3089\u306a\u3044<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec01-01\">\u98df\u6b32\u304c\u5909\u308f\u3063\u3066\u3082\u4f53\u91cd\u304c\u6e1b\u308b\u6642\u671f\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b<\/h3>\n<p><strong><span class=\"marker\">\u98df\u6b32\u304c\u5909\u308f\u3063\u305f\u3068\u611f\u3058\u3066\u3082\u3001\u4f53\u91cd\u304c\u6e1b\u308a\u59cb\u3081\u308b\u6642\u671f\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u904e\u4f53\u91cd\u30fb\u80a5\u6e80\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u98df\u6b32\u3084\u6e80\u8179\u611f\u306e\u5909\u5316\u3092\u8abf\u3079\u305f\u77ed\u671f\u8a66\u9a13\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u7814\u7a76\u6761\u4ef6<\/th>\n<th>\u5185\u5bb9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u5bfe\u8c61<\/th>\n<td>\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u904e\u4f53\u91cd\u30fb\u80a5\u6e80\u306e\u6210\u4eba<\/td>\n<\/tr>\n<tr>\n<th>\u4eba\u6570<\/th>\n<td>114\u4eba<\/td>\n<\/tr>\n<tr>\n<th>\u8a55\u4fa1\u6642\u70b9<\/th>\n<td>\u6295\u4e0e3\u9031<\/td>\n<\/tr>\n<tr>\n<th>\u78ba\u8a8d\u3055\u308c\u305f\u5909\u5316<\/th>\n<td>\u98df\u6b32\u30fb\u7a7a\u8179\u6642\u306e\u6e80\u8179\u611f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u6295\u4e0e3\u9031\u306f\u7814\u7a76\u3067\u5909\u5316\u3092\u8abf\u3079\u305f\u6642\u70b9\u3067\u3042\u308a\u3001\u5168\u54e1\u304c\u305d\u306e\u65e5\u306b\u52b9\u679c\u3092\u611f\u3058\u59cb\u3081\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u307e\u305f\u3001\u98df\u6b32\u306e\u5909\u5316\u304c\u4f53\u91cd\u6e1b\u5c11\u3088\u308a\u5148\u306b\u8d77\u3053\u308b\u3068\u65ad\u5b9a\u3067\u304d\u308b\u7d50\u679c\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u300c3\u9031\u3067\u98df\u6b32\u304c\u5909\u308f\u3063\u305f\u300d\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u3092\u3001\u300c3\u9031\u9593\u5f85\u3066\u3070\u5fc5\u305a\u75e9\u305b\u308b\u300d\u3068\u8aad\u307f\u66ff\u3048\u306a\u3044\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-attention\">\n<div class=\"ac-attention__head\">\n<div class=\"ac-attention__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-attention__title\">\u98df\u6b32\u3068\u4f53\u91cd\u306f\u5225\u3005\u306b\u8a18\u9332<\/span><\/p>\n<\/div>\n<div class=\"ac-attention__body\">\n<p>\u9593\u98df\u306e\u56de\u6570\u3084\u98df\u3079\u7d42\u3048\u305f\u5f8c\u306e\u6e80\u8179\u611f\u3092\u3001\u4f53\u91cd\u3068\u5206\u3051\u3066\u30e1\u30e2\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u8a3a\u5bdf\u3067\u306f\u3001\u98df\u6b32\u304c\u5909\u308f\u3063\u305f\u6642\u671f\u3068\u4f53\u91cd\u306e\u63a8\u79fb\u3092\u305d\u308c\u305e\u308c\u4f1d\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41591-025-03774-9\">Nature Medicine\uff1a\u98df\u884c\u52d5\u3092\u8abf\u3079\u305f6\u9031\u9593\u306e\u7b2c1\u76f8\u8a66\u9a13<\/a>\u3002<\/small><\/p>\n<p>\u7814\u7a76\u3067\u306f\u6700\u521d\u306e3\u9031\u9593\u306b5mg\u3001\u305d\u306e\u5f8c\u306e3\u9031\u9593\u306b10mg\u3092\u4f7f\u7528\u3057\u3066\u304a\u308a\u3001\u65e5\u672c\u306e\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u901a\u5e38\u306e\u958b\u59cb\u7528\u91cf\u3068\u306f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/aclinic.jp\/column\/manjaro-koka\/\">\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u52b9\u679c\u306f\u3044\u3064\u304b\u3089\uff1f\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u3068\u52b9\u679c\u304c\u51fa\u306a\u3044\u7406\u7531\u3092\u89e3\u8aac<\/a><\/p>\n<h3 id=\"sec01-02\">\u6295\u4e0e\u958b\u59cb\u304b\u30891\u9031\u9593\u3067\u4f53\u91cd\u304c\u6e1b\u308b\u3068\u306f\u9650\u3089\u306a\u3044<\/h3>\n<p><strong><span class=\"marker\">\u6295\u4e0e\u958b\u59cb\u304b\u30891\u9031\u9593\u3067\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u304f\u3066\u3082\u3001\u52b9\u679c\u304c\u306a\u3044\u3068\u306f\u5224\u65ad\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u56fd\u5185\u306e\u96fb\u5b50\u6dfb\u6587\u306b\u8a18\u8f09\u3055\u308c\u305f\u3001\u901a\u5e38\u306e\u958b\u59cb\u7528\u91cf\u3068\u5897\u91cf\u306e\u6d41\u308c\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u4f7f\u7528\u6642\u671f<\/th>\n<th>\u901a\u5e38\u306e\u7528\u91cf<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u958b\u59cb\u304b\u30894\u9031\u9593<\/th>\n<td>\u90311\u56de2.5mg<\/td>\n<\/tr>\n<tr>\n<th>4\u9031\u9593\u6295\u4e0e\u3057\u305f\u5f8c<\/th>\n<td>\u90311\u56de5mg\u3078\u5897\u91cf<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u958b\u59cb\u76f4\u5f8c\u306f\u3001\u4f53\u91cd\u3060\u3051\u3067\u306a\u304f\u526f\u4f5c\u7528\u306e\u6709\u7121\u3082\u78ba\u8a8d\u3059\u308b\u6642\u671f\u3067\u3059\u3002<\/p>\n<p>\u6700\u521d\u304b\u30895mg\u3092\u4f7f\u3046\u65b9\u6cd5\u3067\u306f\u306a\u3044\u305f\u3081\u3001\u958b\u59cb1\u9031\u9593\u306e\u4f53\u91cd\u5909\u5316\u3060\u3051\u3067\u3001\u4eca\u5f8c\u306e\u6cbb\u7642\u52b9\u679c\u307e\u3067\u7d50\u8ad6\u3065\u3051\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">1\u9031\u9593\u3067\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u304f\u3066\u3082\u3001\u6ce8\u5c04\u306e\u56de\u6570\u3084\u7528\u91cf\u3092\u81ea\u5df1\u5224\u65ad\u3067\u5897\u3084\u3055\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p>\u4f53\u8abf\u306b\u554f\u984c\u304c\u306a\u3051\u308c\u3070\u51e6\u65b9\u3069\u304a\u308a\u306b\u4f7f\u7528\u3057\u3001\u6b21\u306e\u8a3a\u5bdf\u306b\u6295\u4e0e\u65e5\u3068\u4f53\u91cd\u306e\u8a18\u9332\u3092\u6301\u53c2\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d6\u30fb7\u9805<\/a>\u3002<\/small><\/p>\n<p><a href=\"https:\/\/aclinic.jp\/column\/mj-price\/\">\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5024\u6bb5\u306f\u3044\u304f\u3089\uff1f1\u30f6\u6708\u306e\u76f8\u5834\u30fb\u4fdd\u967a\u9069\u7528\u30fb\u5b89\u304f\u51e6\u65b9\u3057\u3066\u3082\u3089\u3046\u65b9\u6cd5\u3092\u89e3\u8aac<\/a><\/p>\n<h2 id=\"sec02\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\uff1f\u30101\u30fb2\u30fb3\u30fb6\u30f6\u6708\u3011<\/h2>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u4f55\u30f6\u6708\u306b\u4f55kg\u75e9\u305b\u308b\u304b\u306f\u3001\u958b\u59cb\u4f53\u91cd\u3084\u7528\u91cf\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u540c\u3058\u4f7f\u7528\u671f\u9593\u3067\u3082\u3001\u5897\u91cf\u306e\u6642\u671f\u3084\u5404\u7528\u91cf\u3092\u4f7f\u3063\u305f\u671f\u9593\u304c\u9055\u3046\u305f\u3081\u3067\u3059\u3002<\/p>\n<p><strong>\u9577\u671f\u8a66\u9a13\u306e\u5e73\u5747\u6e1b\u91cf\u7387\u3092\u6708\u6570\u3067\u5272\u3063\u3066\u3082\u30011\u30f6\u6708\u3054\u3068\u306e\u6e1b\u91cf\u76ee\u5b89\u306b\u306f\u306a\u308a\u307e\u305b\u3093\u3002<\/strong><\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\uff1f\u30101\u30fb2\u30fb3\u30fb6\u30f6\u6708\u3011<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec02-01\">1\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/a><\/li>\n<li><a href=\"#sec02-02\">2\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/a><\/li>\n<li><a href=\"#sec02-03\">3\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/a><\/li>\n<li><a href=\"#sec02-04\">\u534a\u5e74\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec02-01\">1\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/h3>\n<p><strong><span class=\"marker\">\u958b\u59cb1\u30f6\u6708\u3067\u4f55kg\u6e1b\u308b\u304b\u3092\u3001\u5168\u54e1\u306b\u5171\u901a\u3059\u308b\u76ee\u5b89\u3068\u3057\u3066\u793a\u3059\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p><strong>\u901a\u5e38\u306f\u6700\u521d\u306e4\u9031\u9593\u306b2.5mg\u3092\u4f7f\u3046\u305f\u3081\u3001\u300c\u958b\u59cb\u304b\u30891\u30f6\u6708\u300d\u3068\u300c5mg\u30921\u30f6\u6708\u4f7f\u7528\u3057\u305f\u5834\u5408\u300d\u3067\u306f\u7528\u91cf\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/strong><\/p>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/aclinic.jp\/column\/wp-content\/uploads\/\u958b\u59cb1\u30f6\u6708\u30685mg1\u30f6\u6708\u306e\u9055\u3044-\u56f3\u89e3.png\" alt=\"\u958b\u59cb1\u30f6\u6708\u30685mg1\u30f6\u6708\u306e\u9055\u3044 \u56f3\u89e3\" width=\"640\" height=\"360\" class=\"aligncenter size-full wp-image-6517\" \/>\n<p>\u53e3\u30b3\u30df\u306e\u6e1b\u91cf\u5e45\u3092\u898b\u308b\u3068\u304d\u3082\u3001\u3044\u3064\u304b\u3089\u4f55mg\u3092\u4f7f\u3063\u3066\u3044\u305f\u304b\u3092\u78ba\u8a8d\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u958b\u59cb\u4f53\u91cd\u304c\u9055\u3048\u3070\u3001\u540c\u3058\u5272\u5408\u3067\u4f53\u91cd\u304c\u6e1b\u3063\u3066\u3082kg\u6570\u306f\u5909\u308f\u308a\u307e\u3059\u3002<\/p>\n<p>\u305f\u3068\u3048\u30705\uff05\u306e\u6e1b\u5c11\u306f\u3001\u958b\u59cb\u4f53\u91cd60kg\u306a\u30893kg\u300180kg\u306a\u30894kg\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u8a08\u7b97\u306f\u5272\u5408\u3068kg\u306e\u9055\u3044\u3092\u793a\u3059\u4f8b\u3067\u3042\u308a\u30011\u30f6\u6708\u306e\u6e1b\u91cf\u76ee\u5b89\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<div class=\"ac-check\">\n<div class=\"ac-check__head\">\n<div class=\"ac-check__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-check__title\">1\u30f6\u6708\u76ee\u306b\u78ba\u8a8d\u3057\u305f\u3044\u3053\u3068<\/span><\/p>\n<\/div>\n<div class=\"ac-check__body\">\n<p>\u6295\u4e0e\u65e5\u30fb\u4f53\u91cd\u30fb\u98df\u6b32\u30fb\u5410\u304d\u6c17\u3092\u8a18\u9332\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u5410\u304d\u6c17\u306a\u3069\u306e\u80c3\u8178\u75c7\u72b6\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u5897\u91cf\u524d\u306e\u8a3a\u5bdf\u3067\u4f1d\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n<\/div>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d6\u30fb7\u9805<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec02-02\">2\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/h3>\n<p><strong><span class=\"marker\">2\u30f6\u6708\u76ee\u306e\u6e1b\u91cf\u5e45\u3082\u3001\u4f7f\u3063\u3066\u3044\u308b\u7528\u91cf\u3084\u5897\u91cf\u3057\u305f\u6642\u671f\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u540c\u3058\u300c\u4f7f\u75282\u30f6\u6708\u300d\u3067\u3082\u30015mg\u306b\u5897\u91cf\u3057\u305f\u4eba\u3068\u3001\u80c3\u8178\u75c7\u72b6\u3067\u5897\u91cf\u3092\u5ef6\u671f\u3057\u305f\u4eba\u306e\u4f53\u91cd\u5909\u5316\u306f\u5358\u7d14\u306b\u6bd4\u3079\u3089\u308c\u307e\u305b\u3093\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u6bd4\u8f03\u3059\u308b\u6761\u4ef6<\/th>\n<th>\u8a18\u9332\u3059\u308b\u5185\u5bb9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u4f7f\u7528\u671f\u9593<\/th>\n<td>\u6295\u4e0e\u958b\u59cb\u65e5\u30fb\u4e2d\u65ad\u306e\u6709\u7121<\/td>\n<\/tr>\n<tr>\n<th>\u7528\u91cf\u306e\u7d4c\u904e<\/th>\n<td>\u5404\u7528\u91cf\u3092\u4f7f\u3063\u305f\u9031\u6570<\/td>\n<\/tr>\n<tr>\n<th>\u4f53\u91cd\u306e\u5909\u5316<\/th>\n<td>\u958b\u59cb\u6642\u3068\u73fe\u5728\u306e\u4f53\u91cd<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4f53\u91cd\u304c\u3042\u307e\u308a\u5909\u308f\u3089\u306a\u3044\u5834\u5408\u306f\u3001\u3044\u3064\u3001\u3069\u306e\u7528\u91cf\u3092\u4f7f\u3063\u305f\u304b\u3082\u51e6\u65b9\u533b\u306b\u4f1d\u3048\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u300c2.5mg\u30924\u9031\u9593\u3001\u305d\u306e\u5f8c5mg\u30924\u9031\u9593\u4f7f\u3063\u305f\u300d\u306e\u3088\u3046\u306b\u3001\u7528\u91cf\u3054\u3068\u306e\u671f\u9593\u304c\u5206\u304b\u308b\u3068\u3001\u5897\u91cf\u524d\u5f8c\u306e\u4f53\u91cd\u3084\u4f53\u8abf\u3092\u6bd4\u3079\u3089\u308c\u307e\u3059\u3002<\/p>\n<p>\u4e88\u5b9a\u3069\u304a\u308a\u6295\u4e0e\u3067\u304d\u306a\u304b\u3063\u305f\u65e5\u304c\u3042\u308c\u3070\u3001\u305d\u306e\u65e5\u4ed8\u3082\u8a18\u9332\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u3053\u3068\u3092\u7406\u7531\u306b\u3001\u4e88\u5b9a\u3088\u308a\u65e9\u304f\u5897\u91cf\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d7.3\u30fb7.4\u9805<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec02-03\">3\u30f6\u6708\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/h3>\n<p><strong><span class=\"marker\">3\u30f6\u6708\u7d4c\u904e\u3057\u3066\u3082\u3001\u4f53\u91cd\u3060\u3051\u3067\u306f\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u6cbb\u7642\u52b9\u679c\u3092\u5224\u65ad\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u56fd\u5185\u306e\u627f\u8a8d\u9069\u5fdc\u306f2\u578b\u7cd6\u5c3f\u75c5\u3067\u3059\u3002<\/p>\n<p>\u96fb\u5b50\u6dfb\u6587\u3067\u306f\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u30673\u301c4\u30f6\u6708\u4f7f\u3063\u3066\u3082\u52b9\u679c\u304c\u4e0d\u5341\u5206\u306a\u5834\u5408\u306f\u3001\u6cbb\u7642\u306e\u5909\u66f4\u3092\u691c\u8a0e\u3059\u308b\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u52b9\u679c\u306f\u3001\u5b9a\u671f\u7684\u306a\u8840\u7cd6\u30fb\u5c3f\u7cd6\u306e\u691c\u67fb\u306a\u3069\u3067\u78ba\u304b\u3081\u307e\u3059\u3002<\/p>\n<p>\u4f53\u91cd\u304c\u6e1b\u3063\u3066\u3044\u306a\u3044\u3053\u3068\u3060\u3051\u3067\u3001\u8840\u7cd6\u3092\u6539\u5584\u3059\u308b\u52b9\u679c\u307e\u3067\u5426\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<div class=\"ac-attention\">\n<div class=\"ac-attention__head\">\n<div class=\"ac-attention__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-attention__title\">3\u30f6\u6708\u3092\u300c\u6e1b\u91cf\u306e\u671f\u9650\u300d\u306b\u3057\u306a\u3044<\/span><\/p>\n<\/div>\n<div class=\"ac-attention__body\">\n<p>\u96fb\u5b50\u6dfb\u6587\u306e\u300c3\u301c4\u30f6\u6708\u300d\u306f\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306e\u52b9\u679c\u3092\u898b\u76f4\u3059\u671f\u9593\u3067\u3059\u3002<\/p>\n<p>\u300c3\u30f6\u6708\u3067\u4f55kg\u6e1b\u3089\u3059\u300d\u300c\u75e9\u305b\u306a\u3051\u308c\u3070\u4e2d\u6b62\u3059\u308b\u300d\u3068\u3044\u3046\u6e1b\u91cf\u306e\u57fa\u6e96\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<\/div>\n<\/div>\n<p>\u6e1b\u91cf\u76ee\u7684\u3067\u4f7f\u3063\u3066\u3044\u3066\u671f\u5f85\u3057\u305f\u5909\u5316\u304c\u306a\u3044\u5834\u5408\u3082\u3001\u8ffd\u52a0\u8cfc\u5165\u306e\u524d\u306b\u3001\u6cbb\u7642\u3092\u7d9a\u3051\u308b\u304b\u3069\u3046\u304b\u3092\u51e6\u65b9\u533b\u3068\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d4\u30fb8.2\u9805<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec02-04\">\u534a\u5e74\u3067\u4f55\u30ad\u30ed\u75e9\u305b\u308b\u304b\u306e\u76ee\u5b89<\/h3>\n<p><strong><span class=\"marker\">72\u9031\u306e\u7814\u7a76\u7d50\u679c\u304b\u3089\u3001\u534a\u5e74\u3067\u4f55kg\u75e9\u305b\u308b\u304b\u3092\u8a08\u7b97\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>SURMOUNT-1\u306f\u3001\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u80a5\u6e80\u306e\u6210\u4eba\u3001\u307e\u305f\u306f\u4f53\u91cd\u306b\u95a2\u9023\u3059\u308b\u5408\u4f75\u75c7\u304c\u3042\u308b\u904e\u4f53\u91cd\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8a66\u9a13\u3067\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u7dad\u6301\u7528\u91cf<\/th>\n<th>72\u9031\u6642\u70b9\u306e\u5e73\u5747\u4f53\u91cd\u5909\u5316\u7387<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>5mg<\/th>\n<td>\u221215.0\uff05<\/td>\n<\/tr>\n<tr>\n<th>10mg<\/th>\n<td>\u221219.5\uff05<\/td>\n<\/tr>\n<tr>\n<th>15mg<\/th>\n<td>\u221220.9\uff05<\/td>\n<\/tr>\n<tr>\n<th>\u30d7\u30e9\u30bb\u30dc<\/th>\n<td>\u22123.1\uff05<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small>\u5bfe\u8c61\u306f\u6210\u4eba2,539\u4eba\u3001BMI30\u4ee5\u4e0a\u3001\u307e\u305f\u306fBMI27\u4ee5\u4e0a\u3067\u4f53\u91cd\u95a2\u9023\u306e\u5408\u4f75\u75c7\u304c\u3042\u308b\u4eba\u3067\u3059\u3002<\/small><\/p>\n<p>\u7d50\u679c\u306f\u3001\u98df\u4e8b\u30fb\u904b\u52d5\u306e\u6307\u5c0e\u3068\u6bb5\u968e\u7684\u306a\u5897\u91cf\u3092\u542b\u3080\u8a66\u9a13\u3067\u306e\u5e73\u5747\u5024\u3067\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2206038\">SURMOUNT-1\u539f\u8457\uff1a72\u9031\u306e\u4e3b\u8981\u8a55\u4fa1\u7d50\u679c<\/a>\u3002<\/p>\n<p>72\u9031\u306f\u7d041\u5e745\u30f6\u6708\u306b\u3042\u305f\u308a\u3001\u534a\u5e74\u3088\u308a\u9577\u3044\u671f\u9593\u3067\u3059\u3002<\/p>\n<p>\u8868\u306e\u300c\u221215.0\uff05\u300d\u306f\u30015mg\u7fa4\u306e72\u9031\u6642\u70b9\u306e\u5e73\u5747\u5024\u3067\u3001\u534a\u5e74\u306e\u7d50\u679c\u3067\u3082\u6bce\u6708\u306e\u6e1b\u91cf\u7387\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u307e\u305f\u3001\u8a66\u9a13\u306e\u53c2\u52a0\u8005\u306f\u80a5\u6e80\u307e\u305f\u306f\u5408\u4f75\u75c7\u3092\u4f34\u3046\u904e\u4f53\u91cd\u306e\u6210\u4eba\u3067\u3042\u308a\u3001\u4f53\u683c\u3084\u5065\u5eb7\u72b6\u614b\u304c\u7570\u306a\u308b\u4eba\u306b\u305d\u306e\u307e\u307e\u5f53\u3066\u306f\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p>\u534a\u5e74\u306e\u8a3a\u5bdf\u3067\u306f\u3001\u958b\u59cb\u6642\u304b\u3089\u306e\u4f53\u91cd\u306e\u5909\u5316\u3068\u6cbb\u7642\u4e2d\u306e\u4f53\u8abf\u3092\u51e6\u65b9\u533b\u306b\u4f1d\u3048\u3001\u6cbb\u7642\u3092\u7d9a\u3051\u308b\u304b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<h2 id=\"sec03\">\u30de\u30f3\u30b8\u30e3\u30ed5mg\u30921\u30f6\u6708\u7d99\u7d9a\u3057\u305f\u5834\u5408\u306e\u52b9\u679c<\/h2>\n<p><strong><span class=\"marker\">5mg\u30921\u30f6\u6708\u4f7f\u3063\u305f\u5834\u5408\u3082\u3001\u5168\u54e1\u306b\u5f53\u3066\u306f\u307e\u308b\u6e1b\u91cf\u5e45\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u4f7f\u7528\u671f\u9593\u3092\u6bd4\u3079\u308b\u3068\u304d\u306f\u3001\u6295\u4e0e\u958b\u59cb\u65e5\u30685mg\u3078\u5897\u91cf\u3057\u305f\u65e5\u3092\u533a\u5225\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u901a\u5e38\u3069\u304a\u308a2.5mg\u30924\u9031\u9593\u4f7f\u3063\u305f\u5f8c\u306b5mg\u30924\u9031\u9593\u4f7f\u3063\u305f\u5834\u5408\u3001\u6cbb\u7642\u958b\u59cb\u304b\u3089\u306f\u5408\u8a088\u9031\u9593\u3067\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed5mg\u30921\u30f6\u6708\u7d99\u7d9a\u3057\u305f\u5834\u5408\u306e\u52b9\u679c<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec03-01\">5mg\u30921\u30f6\u6708\u4f7f\u3063\u305f\u5834\u5408\u306e\u6e1b\u91cf\u5e45\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b<\/a><\/li>\n<li><a href=\"#sec03-02\">2.5mg\u304b\u3089\u306e\u5897\u91cf\u306f\u4f53\u91cd\u3068\u4f53\u8abf\u3092\u8e0f\u307e\u3048\u3066\u533b\u5e2b\u304c\u6c7a\u3081\u308b<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec03-01\">5mg\u30921\u30f6\u6708\u4f7f\u3063\u305f\u5834\u5408\u306e\u6e1b\u91cf\u5e45\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b<\/h3>\n<p><strong><span class=\"marker\">\u9577\u671f\u8a66\u9a13\u306e\u7d50\u679c\u306f\u3001\u300c5mg\u30921\u30f6\u6708\u4f7f\u3048\u3070\u4f55kg\u75e9\u305b\u308b\u304b\u300d\u306e\u76ee\u5b89\u306b\u306f\u4f7f\u3048\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>SURMOUNT-1\u306e\u300c5mg\u7fa4\u300d\u306f\u30012.5mg\u304b\u30895mg\u3078\u5897\u91cf\u3057\u3001\u6295\u4e0e\u958b\u59cb\u304b\u308972\u9031\u307e\u3067\u8a55\u4fa1\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u3059\u3002<\/p>\n<p><strong>\u300c5mg\u3092\u4f7f\u3044\u59cb\u3081\u30661\u30f6\u6708\u306715\uff05\u6e1b\u308b\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong><\/p>\n<p>5mg\u3078\u5897\u91cf\u3057\u305f\u65e5\u306e\u4f53\u91cd\u3068\u3001\u305d\u306e\u5f8c\u306e\u8a18\u9332\u3092\u6bd4\u3079\u308b\u3068\u3001\u5897\u91cf\u5f8c\u306e\u5909\u5316\u3092\u6574\u7406\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u6cbb\u7642\u958b\u59cb\u304b\u3089\u306e\u5909\u5316\u3082\u5225\u306b\u6b8b\u3057\u3066\u304a\u3051\u3070\u30012.5mg\u3092\u4f7f\u3063\u3066\u3044\u305f\u671f\u9593\u30685mg\u3092\u4f7f\u3063\u305f\u671f\u9593\u3092\u6df7\u540c\u305b\u305a\u306b\u4f1d\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">5mg\u306e\u52b9\u679c\u3092\u76f8\u8ac7\u3059\u308b\u3068\u304d\u306e\u8a18\u9332<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li>5mg\u3078\u5897\u91cf\u3057\u305f\u65e5\u3068\u6295\u4e0e\u56de\u6570<\/li>\n<li>\u5897\u91cf\u524d\u5f8c\u306e\u4f53\u91cd\u3068\u98df\u6b32<\/li>\n<li>\u5410\u304d\u6c17\u30fb\u5614\u5410\u30fb\u4fbf\u901a\u306e\u5909\u5316<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p><strong><span style=\"color: #ff0000;\">\u98df\u4e8b\u3084\u6c34\u5206\u304c\u53d6\u308c\u3066\u3044\u306a\u3044\u5834\u5408\u306f\u3001\u6e1b\u91cf\u5e45\u306b\u304b\u304b\u308f\u3089\u305a\u3001\u307e\u305a\u4f53\u8abf\u306b\u3064\u3044\u3066\u51e6\u65b9\u533b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2206038\">SURMOUNT-1\u539f\u8457\uff1a\u6295\u4e0e\u65b9\u6cd5\u30fb72\u9031\u306e\u7d50\u679c<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec03-02\">2.5mg\u304b\u3089\u306e\u5897\u91cf\u306f\u4f53\u91cd\u3068\u4f53\u8abf\u3092\u8e0f\u307e\u3048\u3066\u533b\u5e2b\u304c\u6c7a\u3081\u308b<\/h3>\n<p><strong><span class=\"marker\">2.5mg\u304b\u3089\u5897\u91cf\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u3001\u4f53\u91cd\u306e\u5909\u5316\u3060\u3051\u3067\u306a\u304f\u526f\u4f5c\u7528\u3082\u8e0f\u307e\u3048\u3066\u533b\u5e2b\u304c\u5224\u65ad\u3057\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u96fb\u5b50\u6dfb\u6587\u3067\u306f\u3001\u80c3\u8178\u75c7\u72b6\u304c\u3064\u3089\u3044\u5834\u5408\u306f\u3001\u7528\u91cf\u3092\u6e1b\u3089\u3059\u3053\u3068\u3084\u5897\u91cf\u306e\u5ef6\u671f\u3092\u691c\u8a0e\u3059\u308b\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4f53\u91cd\u306e\u6e1b\u308a\u65b9\u306b\u3082\u6ce8\u610f\u3057\u3001\u5897\u91cf\u304c\u5fc5\u8981\u304b\u614e\u91cd\u306b\u5224\u65ad\u3059\u308b\u3088\u3046\u6c42\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>5mg\u3067\u52b9\u679c\u304c\u4e0d\u5341\u5206\u306a\u5834\u5408\u306e\u8ffd\u52a0\u5897\u91cf\u3082\u3001\u96fb\u5b50\u6dfb\u6587\u3067\u306f4\u9031\u9593\u4ee5\u4e0a\u306e\u9593\u9694\u3092\u7a7a\u3051\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u5897\u91cf\u3067\u304d\u308b\u6642\u671f\u3092\u8fce\u3048\u3066\u3082\u3001\u5fc5\u305a\u5897\u3084\u3059\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u533b\u5e2b\u304c\u52b9\u679c\u3068\u526f\u4f5c\u7528\u3092\u78ba\u8a8d\u3057\u3066\u6c7a\u3081\u307e\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u8a3a\u5bdf\u3067\u4f1d\u3048\u308b\u3053\u3068<\/th>\n<th>\u5177\u4f53\u7684\u306a\u5185\u5bb9<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u80c3\u8178\u75c7\u72b6<\/th>\n<td>\u5410\u304d\u6c17\u30fb\u5614\u5410\u306e\u983b\u5ea6<\/td>\n<\/tr>\n<tr>\n<th>\u98df\u4e8b\u30fb\u6c34\u5206<\/th>\n<td>\u6442\u53d6\u3067\u304d\u3066\u3044\u308b\u91cf<\/td>\n<\/tr>\n<tr>\n<th>\u6cbb\u7642\u306e\u7d4c\u904e<\/th>\n<td>\u4f53\u91cd\u30fb\u8840\u7cd6\u30fb\u4f75\u7528\u85ac<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u5410\u304d\u6c17\u304c\u7d9a\u304f\u5834\u5408\u306f\u3001\u5897\u91cf\u4e88\u5b9a\u65e5\u524d\u306b\u51e6\u65b9\u533b\u3078\u9023\u7d61\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">\u65e9\u304f\u75e9\u305b\u305f\u3044\u5834\u5408\u3082\u3001\u51e6\u65b9\u3055\u308c\u305f\u7528\u91cf\u3092\u81ea\u5df1\u5224\u65ad\u3067\u5909\u3048\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d6\u30fb7.3\u30fb7.4\u9805<\/a>\u3002<\/small><\/p>\n<h2 id=\"sec04\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u59cb\u3081\u3066\u3044\u308b\u30b5\u30a4\u30f3<\/h2>\n<p><strong><span class=\"marker\">\u98df\u6b32\u3084\u6e80\u8179\u611f\u304c\u5909\u308f\u3063\u3066\u3082\u3001\u305d\u308c\u3060\u3051\u3067\u306f\u4f53\u8102\u80aa\u304c\u6e1b\u3063\u305f\u3068\u306f\u5224\u65ad\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u4f53\u91cd\u306e\u63a8\u79fb\u306b\u52a0\u3048\u3001\u5410\u304d\u6c17\u306a\u3069\u3067\u98df\u3079\u3089\u308c\u306a\u304f\u306a\u3063\u3066\u3044\u306a\u3044\u304b\u3082\u78ba\u8a8d\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u59cb\u3081\u3066\u3044\u308b\u30b5\u30a4\u30f3<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec04-01\">\u98df\u6b32\u3084\u6e80\u8179\u611f\u306e\u5909\u5316\u3060\u3051\u3067\u306f\u4f53\u8102\u80aa\u306e\u6e1b\u5c11\u306f\u5206\u304b\u3089\u306a\u3044<\/a><\/li>\n<li><a href=\"#sec04-02\">\u4f53\u91cd\u306f\u540c\u3058\u6761\u4ef6\u3067\u6e2c\u308a\u3001\u6570\u65e5\u9593\u306e\u5897\u6e1b\u3060\u3051\u3067\u5224\u65ad\u3057\u306a\u3044<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec04-01\">\u98df\u6b32\u3084\u6e80\u8179\u611f\u306e\u5909\u5316\u3060\u3051\u3067\u306f\u4f53\u8102\u80aa\u306e\u6e1b\u5c11\u306f\u5206\u304b\u3089\u306a\u3044<\/h3>\n<p><strong><span class=\"marker\">\u7a7a\u8179\u3092\u611f\u3058\u306b\u304f\u304f\u306a\u3063\u305f\u308a\u3001\u9593\u98df\u3057\u305f\u3044\u6c17\u6301\u3061\u304c\u6e1b\u3063\u305f\u308a\u3057\u305f\u5834\u5408\u306f\u3001\u4f53\u91cd\u3068\u4e00\u7dd2\u306b\u8a18\u9332\u3057\u307e\u3057\u3087\u3046\u3002<\/span><\/strong><\/p>\n<p>\u98df\u6b32\u3084\u7a7a\u8179\u6642\u306e\u6e80\u8179\u611f\u306e\u5909\u5316\u306f\u77ed\u671f\u8a66\u9a13\u3067\u3082\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u305f\u3060\u3057\u3001\u98df\u6b32\u306e\u5909\u5316\u304b\u3089\u4f53\u8102\u80aa\u304c\u3069\u308c\u3060\u3051\u6e1b\u3063\u305f\u304b\u306f\u5206\u304b\u308a\u307e\u305b\u3093\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u78ba\u8a8d\u3059\u308b\u5909\u5316<\/th>\n<th>\u30e1\u30e2\u306e\u4f8b<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u9593\u98df\u3078\u306e\u6b32\u6c42<\/th>\n<td>\u9593\u98df\u306e\u56de\u6570\u30fb\u98df\u3079\u305f\u3044\u6642\u9593\u5e2f<\/td>\n<\/tr>\n<tr>\n<th>\u98df\u5f8c\u306e\u6e80\u8179\u611f<\/th>\n<td>\u98df\u3079\u305f\u91cf\u3068\u6e80\u8179\u611f<\/td>\n<\/tr>\n<tr>\n<th>\u98df\u3079\u3065\u3089\u3055<\/th>\n<td>\u5410\u304d\u6c17\u306e\u6709\u7121\u30fb\u6c34\u5206\u6442\u53d6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong><span style=\"color: #ff0000;\">\u5410\u304d\u6c17\u3067\u98df\u3079\u3089\u308c\u306a\u3044\u72b6\u614b\u3092\u3001\u9806\u8abf\u306b\u75e9\u305b\u3066\u3044\u308b\u30b5\u30a4\u30f3\u3068\u8003\u3048\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p>\u5614\u5410\u3084\u4e0b\u75e2\u304c\u7d9a\u304f\u5834\u5408\u306f\u3001\u75c7\u72b6\u304c\u59cb\u307e\u3063\u305f\u6642\u671f\u3084\u98f2\u3081\u3066\u3044\u308b\u6c34\u5206\u91cf\u3092\u51e6\u65b9\u533b\u306b\u4f1d\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u96fb\u5b50\u6dfb\u6587\u3067\u306f\u3001\u5614\u5410\u3084\u4e0b\u75e2\u306b\u7d9a\u304f\u8131\u6c34\u304b\u3089\u3001\u6025\u6027\u814e\u969c\u5bb3\u306b\u81f3\u308b\u304a\u305d\u308c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u4f53\u91cd\u304c\u6e1b\u3063\u3066\u3044\u3066\u3082\u3001\u6c34\u5206\u3092\u53d6\u308c\u306a\u3044\u72b6\u614b\u3092\u6e1b\u91cf\u306e\u6210\u679c\u3068\u8003\u3048\u3066\u653e\u7f6e\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41591-025-03774-9\">Nature Medicine\uff1a\u98df\u6b32\u30fb\u98df\u884c\u52d5\u306e\u77ed\u671f\u8a66\u9a13<\/a>\uff0f<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d8.12\u30fb11\u9805<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec04-02\">\u4f53\u91cd\u306f\u540c\u3058\u6761\u4ef6\u3067\u6e2c\u308a\u3001\u6570\u65e5\u9593\u306e\u5897\u6e1b\u3060\u3051\u3067\u5224\u65ad\u3057\u306a\u3044<\/h3>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/aclinic.jp\/column\/wp-content\/uploads\/\u540c\u3058\u6761\u4ef6\u3067\u4f53\u91cd\u3092\u8a18\u9332-\u56f3\u89e3.png\" alt=\"\u540c\u3058\u6761\u4ef6\u3067\u4f53\u91cd\u3092\u8a18\u9332 \u56f3\u89e3\" width=\"640\" height=\"360\" class=\"aligncenter size-full wp-image-6519\" \/>\n<p><strong><span class=\"marker\">\u4f53\u91cd\u306f\u540c\u3058\u6761\u4ef6\u3067\u6e2c\u308a\u3001\u6570\u65e5\u9593\u306e\u5897\u6e1b\u3060\u3051\u3067\u52b9\u679c\u3092\u5224\u65ad\u3057\u306a\u3044\u3088\u3046\u306b\u3057\u307e\u3057\u3087\u3046\u3002<\/span><\/strong><\/p>\n<p><strong>\u98df\u4e8b\u3084\u6c34\u5206\u306e\u6442\u53d6\u3001\u6392\u6cc4\u306a\u3069\u3067\u4f53\u91cd\u306f\u5909\u52d5\u3057\u307e\u3059\u3002<\/strong><\/p>\n<p>\u6e2c\u308b\u6642\u9593\u3084\u670d\u88c5\u3092\u305d\u308d\u3048\u308b\u3068\u3001\u4f53\u91cd\u306e\u5909\u5316\u3092\u6bd4\u3079\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u4f53\u91cd\u8a18\u9332\u306e\u6761\u4ef6\u3092\u305d\u308d\u3048\u308b<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li>\u540c\u3058\u4f53\u91cd\u8a08\u3092\u3001\u786c\u304f\u5e73\u3089\u306a\u5e8a\u3067\u4f7f\u3046<\/li>\n<li>\u3067\u304d\u308b\u3060\u3051\u540c\u3058\u6642\u9593\u5e2f\u3001\u540c\u7a0b\u5ea6\u306e\u670d\u88c5\u3067\u6e2c\u308b<\/li>\n<li>\u6e2c\u5b9a\u65e5\u30fb\u4f53\u91cd\u30fb\u6295\u4e0e\u65e5\u3092\u8a18\u9332\u3059\u308b<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p>\u6e2c\u5b9a\u983b\u5ea6\u306f\u51e6\u65b9\u533b\u306e\u6307\u793a\u306b\u5408\u308f\u305b\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u6bce\u65e5\u6e2c\u308b\u5834\u5408\u3082\u3001\u305d\u306e\u65e5\u306e\u5897\u6e1b\u306b\u5408\u308f\u305b\u3066\u98df\u4e8b\u3084\u85ac\u306e\u91cf\u3092\u5909\u3048\u305a\u3001\u8a3a\u5bdf\u306b\u8a18\u9332\u3092\u6301\u53c2\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u305f\u3068\u3048\u3070\u671d\u3068\u591c\u306e\u6570\u5024\u304c\u9055\u3063\u3066\u3082\u3001\u305d\u306e\u5dee\u304c\u3059\u3079\u3066\u4f53\u8102\u80aa\u306e\u5897\u6e1b\u3092\u793a\u3059\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u6295\u4e0e\u65e5\u3084\u4fbf\u901a\u3001\u98df\u4e8b\u30fb\u6c34\u5206\u3092\u53d6\u308c\u305f\u304b\u3082\u4f53\u91cd\u306e\u6a2a\u306b\u30e1\u30e2\u3059\u308b\u3068\u3001\u4f53\u8abf\u306e\u5909\u5316\u3068\u4e00\u7dd2\u306b\u632f\u308a\u8fd4\u308c\u307e\u3059\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.england.nhs.uk\/long-read\/how-to-record-your-weight\/\">NHS England\uff1a\u4f53\u91cd\u3092\u8a18\u9332\u3059\u308b\u65b9\u6cd5<\/a>\uff0f<a href=\"https:\/\/health.clevelandclinic.org\/weight-fluctuations\">Cleveland Clinic\uff1a\u4f53\u91cd\u304c\u77ed\u671f\u9593\u3067\u5909\u52d5\u3059\u308b\u8981\u56e0<\/a>\u3002<\/small><\/p>\n<h2 id=\"sec05\">\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u3063\u3066\u3082\u75e9\u305b\u306a\u3044\u7406\u7531<\/h2>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u539f\u56e0\u306f\u3001\u7528\u91cf\u4e0d\u8db3\u3060\u3051\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u98df\u4e8b\u3084\u6d3b\u52d5\u91cf\u3001\u6295\u4e0e\u306e\u8a18\u9332\u3092\u898b\u76f4\u3059\u3068\u3001\u8a3a\u5bdf\u3067\u539f\u56e0\u3092\u76f8\u8ac7\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u3063\u3066\u3082\u75e9\u305b\u306a\u3044\u7406\u7531<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec05-01\">\u85ac\u3078\u306e\u53cd\u5fdc\u3084\u98df\u4e8b\u30fb\u6d3b\u52d5\u91cf\u3082\u4f53\u91cd\u306b\u5f71\u97ff\u3059\u308b<\/a><\/li>\n<li><a href=\"#sec05-02\">\u4f53\u91cd\u304c\u505c\u6ede\u3057\u3066\u3082\u81ea\u5df1\u5224\u65ad\u3067\u5897\u91cf\u3057\u306a\u3044<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec05-01\">\u85ac\u3078\u306e\u53cd\u5fdc\u3084\u98df\u4e8b\u30fb\u6d3b\u52d5\u91cf\u3082\u4f53\u91cd\u306b\u5f71\u97ff\u3059\u308b<\/h3>\n<p><strong><span class=\"marker\">\u85ac\u3078\u306e\u53cd\u5fdc\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u98df\u4e8b\u3084\u6d3b\u52d5\u91cf\u3082\u4f53\u91cd\u306b\u5f71\u97ff\u3057\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u98df\u6b32\u304c\u5909\u308f\u3063\u305f\u304b\u3069\u3046\u304b\u306b\u52a0\u3048\u3001\u5b9f\u969b\u306e\u98df\u4e8b\u91cf\u3084\u65e5\u5e38\u306e\u6d3b\u52d5\u91cf\u3092\u632f\u308a\u8fd4\u308a\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u4f53\u5185\u306e\u6c34\u5206\u91cf\u306a\u3069\u306b\u3088\u308b\u77ed\u671f\u7684\u306a\u5897\u6e1b\u3082\u3042\u308b\u305f\u3081\u30011\u56de\u306e\u6e2c\u5b9a\u7d50\u679c\u304b\u3089\u539f\u56e0\u3092\u6c7a\u3081\u3064\u3051\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u78ba\u8a8d\u3059\u308b\u6761\u4ef6<\/th>\n<th>\u898b\u76f4\u3059\u30dd\u30a4\u30f3\u30c8<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u4f7f\u7528\u5c65\u6b74<\/th>\n<td>\u7528\u91cf\u30fb\u6295\u4e0e\u65e5\u30fb\u4e2d\u65ad<\/td>\n<\/tr>\n<tr>\n<th>\u98df\u4e8b<\/th>\n<td>\u98df\u4e8b\u91cf\u30fb\u9593\u98df\u30fb\u98f2\u6599<\/td>\n<\/tr>\n<tr>\n<th>\u6d3b\u52d5\u91cf<\/th>\n<td>\u6b69\u304f\u6642\u9593\u30fb\u4ed5\u4e8b\u4e2d\u306e\u52d5\u304d<\/td>\n<\/tr>\n<tr>\n<th>\u6e2c\u5b9a\u6761\u4ef6<\/th>\n<td>\u6642\u9593\u5e2f\u30fb\u670d\u88c5\u30fb\u4f53\u91cd\u8a08<\/td>\n<\/tr>\n<tr>\n<th>\u4f53\u8abf<\/th>\n<td>\u4fbf\u901a\u30fb\u3080\u304f\u307f\u30fb\u80c3\u8178\u75c7\u72b6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u7406\u7531\u3092\u3001\u672c\u4eba\u306e\u52aa\u529b\u4e0d\u8db3\u3068\u6c7a\u3081\u3064\u3051\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u98df\u4e8b\u3092\u6975\u7aef\u306b\u6e1b\u3089\u3059\u524d\u306b\u3001\u4f53\u91cd\u3084\u98df\u4e8b\u306e\u8a18\u9332\u3092\u51e6\u65b9\u533b\u306b\u898b\u305b\u3001\u898b\u76f4\u305b\u308b\u70b9\u3092\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u8a18\u9332\u306f\u7d30\u304b\u306a\u30ab\u30ed\u30ea\u30fc\u8a08\u7b97\u3060\u3051\u3067\u306a\u304f\u3001\u300c\u9593\u98df\u304c\u5897\u3048\u305f\u300d\u300c\u4ed5\u4e8b\u304c\u5909\u308f\u3063\u3066\u6b69\u304f\u6642\u9593\u304c\u6e1b\u3063\u305f\u300d\u3068\u3044\u3063\u305f\u5909\u5316\u3067\u3082\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2206038\">SURMOUNT-1\u539f\u8457\uff1a\u751f\u6d3b\u7fd2\u6163\u4ecb\u5165\u3092\u542b\u3080\u8a66\u9a13<\/a>\uff0f<a href=\"https:\/\/health.clevelandclinic.org\/weight-fluctuations\">Cleveland Clinic\uff1a\u4f53\u91cd\u304c\u77ed\u671f\u9593\u3067\u5909\u52d5\u3059\u308b\u8981\u56e0<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec05-02\">\u4f53\u91cd\u304c\u505c\u6ede\u3057\u3066\u3082\u81ea\u5df1\u5224\u65ad\u3067\u5897\u91cf\u3057\u306a\u3044<\/h3>\n<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/aclinic.jp\/column\/wp-content\/uploads\/\u30de\u30f3\u30b8\u30e3\u30ed\u76f8\u8ac7\u306e3\u30b9\u30c6\u30c3\u30d7-\u56f3\u89e3.png\" alt=\"\u30de\u30f3\u30b8\u30e3\u30ed\u76f8\u8ac7\u306e3\u30b9\u30c6\u30c3\u30d7 \u56f3\u89e3\" width=\"640\" height=\"308\" class=\"aligncenter size-full wp-image-6518\" \/>\n<p><strong><span class=\"marker\">\u4f53\u91cd\u304c\u505c\u6ede\u3057\u305f\u5834\u5408\u3082\u3001\u81ea\u5df1\u5224\u65ad\u3067\u5897\u91cf\u305b\u305a\u51e6\u65b9\u533b\u306b\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p>\u76f8\u8ac7\u6642\u306b\u306f\u3001\u4f53\u91cd\u304c\u5909\u308f\u3089\u306a\u304f\u306a\u3063\u305f\u6642\u671f\u3068\u3001\u4f7f\u3063\u3066\u3044\u305f\u7528\u91cf\u30fb\u6295\u4e0e\u65e5\u3092\u4f1d\u3048\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-flow\">\n<div class=\"ac-flow__step\">\n<div class=\"ac-flow__label\">STEP1<\/div>\n<div class=\"ac-flow__arrows\" aria-hidden=\"true\"><span class=\"ac-flow__arrow\"><\/span><br \/>\n<span class=\"ac-flow__arrow\"><\/span><br \/>\n<span class=\"ac-flow__arrow\"><\/span><\/div>\n<div class=\"ac-flow__body\">\u4f53\u91cd\u8a18\u9332\u30fb\u7528\u91cf\u30fb\u6295\u4e0e\u65e5\u30fb\u4f53\u8abf\u3092\u307e\u3068\u3081\u308b<\/div>\n<\/div>\n<div class=\"ac-flow__step\">\n<div class=\"ac-flow__label\">STEP2<\/div>\n<div class=\"ac-flow__arrows\" aria-hidden=\"true\"><span class=\"ac-flow__arrow\"><\/span><br \/>\n<span class=\"ac-flow__arrow\"><\/span><br \/>\n<span class=\"ac-flow__arrow\"><\/span><\/div>\n<div class=\"ac-flow__body\">\u51e6\u65b9\u533b\u306b\u3001\u7d99\u7d9a\u30fb\u5897\u91cf\u30fb\u6cbb\u7642\u5909\u66f4\u304c\u5fc5\u8981\u304b\u76f8\u8ac7\u3059\u308b<\/div>\n<\/div>\n<div class=\"ac-flow__step\">\n<div class=\"ac-flow__label\">STEP3<\/div>\n<div class=\"ac-flow__body\">\u4eca\u5f8c\u306e\u6cbb\u7642\u65b9\u91dd\u3068\u6b21\u306e\u8a3a\u5bdf\u6642\u671f\u3092\u78ba\u8a8d\u3059\u308b<\/div>\n<\/div>\n<\/div>\n<p>\u4f53\u91cd\u306e\u505c\u6ede\u3060\u3051\u3067\u4f53\u8abf\u306b\u554f\u984c\u304c\u306a\u3051\u308c\u3070\u3001\u51e6\u65b9\u3069\u304a\u308a\u306e\u4f7f\u7528\u3092\u7d9a\u3051\u306a\u304c\u3089\u76f8\u8ac7\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u8a3a\u5bdf\u3067\u306f\u3001\u7528\u91cf\u3092\u7dad\u6301\u3059\u308b\u306e\u304b\u3001\u5897\u91cf\u3084\u5225\u306e\u6cbb\u7642\u3092\u691c\u8a0e\u3059\u308b\u306e\u304b\u3092\u78ba\u8a8d\u3057\u3001\u6b21\u306b\u3044\u3064\u52b9\u679c\u3092\u898b\u76f4\u3059\u304b\u3082\u6c7a\u3081\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-caution\">\n<div class=\"ac-caution__head\">\n<div class=\"ac-caution__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-caution__title\">\u6fc0\u3057\u3044\u8179\u75db\u306f\u6b21\u56de\u8a3a\u5bdf\u307e\u3067\u5f85\u305f\u306a\u3044<\/span><\/p>\n<\/div>\n<div class=\"ac-caution__body\">\n<p>\u5614\u5410\u3092\u4f34\u3046\u6301\u7d9a\u7684\u306a\u6fc0\u3057\u3044\u8179\u75db\u306f\u3001\u6025\u6027\u81b5\u708e\u306e\u521d\u671f\u75c7\u72b6\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f7f\u7528\u3092\u4e2d\u6b62\u3057\u3001\u901f\u3084\u304b\u306b\u533b\u5e2b\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n<\/div>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d7.4\u30fb8.6\u9805<\/a>\u3002<\/small><\/p>\n<h2 id=\"sec06\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u30f6\u6708\u7d9a\u3051\u308b\uff1f\u3084\u3081\u6642\u306e\u30dd\u30a4\u30f3\u30c8<\/h2>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f55\u30f6\u6708\u3067\u3084\u3081\u308b\u304b\u306f\u3001\u6cbb\u7642\u306e\u76ee\u7684\u3084\u4f53\u8abf\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u958b\u59cb\u6642\u306e\u6cbb\u7642\u76ee\u6a19\u3092\u3082\u3068\u306b\u3001\u7d9a\u3051\u308b\u671f\u9593\u3084\u898b\u76f4\u3059\u6642\u671f\u3092\u51e6\u65b9\u533b\u3068\u6c7a\u3081\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u30f6\u6708\u7d9a\u3051\u308b\uff1f\u3084\u3081\u6642\u306e\u30dd\u30a4\u30f3\u30c8<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec06-01\">\u6cbb\u7642\u671f\u9593\u306f\u52b9\u679c\u30fb\u526f\u4f5c\u7528\u30fb\u6cbb\u7642\u76ee\u6a19\u3092\u3082\u3068\u306b\u533b\u5e2b\u3068\u6c7a\u3081\u308b<\/a><\/li>\n<li><a href=\"#sec06-02\">\u4e2d\u65ad\u30fb\u518d\u958b\u30fb\u5897\u91cf\u306f\u51e6\u65b9\u533b\u306b\u76f8\u8ac7\u3057\u3066\u6c7a\u3081\u308b<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec06-01\">\u6cbb\u7642\u671f\u9593\u306f\u52b9\u679c\u30fb\u526f\u4f5c\u7528\u30fb\u6cbb\u7642\u76ee\u6a19\u3092\u3082\u3068\u306b\u533b\u5e2b\u3068\u6c7a\u3081\u308b<\/h3>\n<p><strong><span class=\"marker\">\u6cbb\u7642\u671f\u9593\u306f\u3001\u4f53\u91cd\u3060\u3051\u3067\u306a\u304f\u6cbb\u7642\u76ee\u7684\u30fb\u52b9\u679c\u30fb\u526f\u4f5c\u7528\u3092\u8e0f\u307e\u3048\u3066\u533b\u5e2b\u3068\u6c7a\u3081\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>\u76ee\u6a19\u4f53\u91cd\u306b\u9054\u3057\u3066\u3082\u3001\u81ea\u5df1\u5224\u65ad\u3067\u4e2d\u6b62\u3059\u308b\u306e\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>SURMOUNT-4\u3067\u306f\u3001\u7cd6\u5c3f\u75c5\u306e\u306a\u3044\u904e\u4f53\u91cd\u30fb\u80a5\u6e80\u306e\u6210\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u3092\u7d9a\u3051\u305f\u5834\u5408\u3068\u4e2d\u6b62\u3057\u305f\u5834\u5408\u306e\u4f53\u91cd\u5909\u5316\u3092\u6bd4\u8f03\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>36\u9031\u5f8c\u306e\u6cbb\u7642<\/th>\n<th>36\u301c88\u9031\u306e\u5e73\u5747\u4f53\u91cd\u5909\u5316\u7387<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\u3092\u7d99\u7d9a<\/th>\n<td>\u22125.5\uff05<\/td>\n<\/tr>\n<tr>\n<th>\u30d7\u30e9\u30bb\u30dc\u3078\u5207\u308a\u66ff\u3048<\/th>\n<td>\uff0b14.0\uff05<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small>\u6700\u521d\u306e36\u9031\u9593\u3067\u3001\u526f\u4f5c\u7528\u306a\u3069\u3092\u8e0f\u307e\u3048\u3066\u7d99\u7d9a\u3067\u304d\u308b\u6700\u5927\u306e\u7528\u91cf\uff0810mg\u307e\u305f\u306f15mg\uff09\u3092\u4f7f\u7528\u3057\u305f\u5f8c\u3001670\u4eba\u30922\u7fa4\u306b\u5206\u3051\u305f\u8a66\u9a13\u3067\u3059\u3002<\/small><\/p>\n<p>\u5272\u5408\u306f\u6295\u4e0e\u958b\u59cb\u6642\u3067\u306f\u306a\u304f\u300136\u9031\u6642\u70b9\u306e\u4f53\u91cd\u3092\u57fa\u6e96\u306b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2812936\">JAMA\uff1aSURMOUNT-4\u539f\u8457<\/a>\u3002<\/p>\n<p>\u4e2d\u6b62\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u5e73\u5747\u4f53\u91cd\u304c\u5897\u3048\u307e\u3057\u305f\u304c\u3001\u500b\u4eba\u306e\u5897\u52a0\u91cf\u3092\u4e88\u6e2c\u3067\u304d\u308b\u7d50\u679c\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p>\u300c\uff0b14.0\uff05\u300d\u306f\u3001\u6cbb\u7642\u3092\u59cb\u3081\u308b\u524d\u306e\u4f53\u91cd\u3067\u306f\u306a\u304f\u300136\u9031\u6642\u70b9\u306e\u4f53\u91cd\u304b\u3089\u306e\u5897\u52a0\u7387\u3067\u3059\u3002<\/p>\n<p>\u6cbb\u7642\u4e2d\u306b\u6e1b\u3063\u305f\u4f53\u91cd\u3092\u7dad\u6301\u3059\u308b\u306b\u306f\u3001\u4e2d\u6b62\u5f8c\u306e\u7d4c\u904e\u3082\u78ba\u8a8d\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4e2d\u6b62\u3092\u8003\u3048\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u305d\u306e\u5f8c\u306e\u98df\u4e8b\u3084\u6d3b\u52d5\u91cf\u3001\u4f53\u91cd\u306e\u7ba1\u7406\u306b\u3064\u3044\u3066\u3082\u76f8\u8ac7\u3057\u3001\u6b21\u306e\u8a3a\u5bdf\u65e5\u3092\u6c7a\u3081\u307e\u3057\u3087\u3046\u3002<\/p>\n<h3 id=\"sec06-02\">\u4e2d\u65ad\u30fb\u518d\u958b\u30fb\u5897\u91cf\u306f\u51e6\u65b9\u533b\u306b\u76f8\u8ac7\u3057\u3066\u6c7a\u3081\u308b<\/h3>\n<p><strong><span class=\"marker\">\u4e88\u5b9a\u5916\u306b\u4e2d\u65ad\u3057\u305f\u5834\u5408\u306f\u3001\u518d\u958b\u3059\u308b\u524d\u306b\u7528\u91cf\u3092\u51e6\u65b9\u533b\u3078\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p>\u518d\u958b\u3092\u76f8\u8ac7\u3059\u308b\u3068\u304d\u306f\u3001\u6700\u5f8c\u306b\u6295\u4e0e\u3057\u305f\u65e5\u3001\u4ee5\u524d\u306e\u7528\u91cf\u3001\u4e2d\u65ad\u3057\u305f\u7406\u7531\u3001\u73fe\u5728\u306e\u4f53\u8abf\u3092\u4f1d\u3048\u307e\u3057\u3087\u3046\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">\u624b\u5143\u306b\u6ce8\u5c04\u304c\u6b8b\u3063\u3066\u3044\u3066\u3082\u3001\u81ea\u5df1\u5224\u65ad\u3067\u518d\u958b\u3084\u5897\u91cf\u3092\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<div class=\"ac-check\">\n<div class=\"ac-check__head\">\n<div class=\"ac-check__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-check__title\">\u7d42\u4e86\u30fb\u518d\u958b\u524d\u306b\u533b\u5e2b\u3068\u6c7a\u3081\u308b\u9805\u76ee<\/span><\/p>\n<\/div>\n<div class=\"ac-check__body\">\n<p>\u518d\u958b\u3059\u308b\u7528\u91cf\u3068\u6295\u4e0e\u65e5\u3001\u6ce8\u610f\u3059\u308b\u75c7\u72b6\u3092\u805e\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u4e2d\u6b62\u3059\u308b\u5834\u5408\u306f\u3001\u4f53\u91cd\u3084\u8840\u7cd6\u3092\u78ba\u8a8d\u3059\u308b\u6642\u671f\u3068\u3001\u5fc5\u8981\u306a\u4ee3\u66ff\u6cbb\u7642\u3082\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n<\/div>\n<p><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4e2d\u6b62\u5f8c\u3082\u85ac\u306e\u4f5c\u7528\u304c\u7d9a\u304f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/p>\n<p>\u4f7f\u7528\u3092\u3084\u3081\u305f\u5f8c\u3082\u3001\u533b\u5e2b\u306e\u6307\u793a\u306b\u5f93\u3063\u3066\u8840\u7cd6\u306e\u5909\u5316\u3084\u526f\u4f5c\u7528\u306b\u6ce8\u610f\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u526f\u4f5c\u7528\u304c\u7406\u7531\u3067\u4e2d\u65ad\u3057\u305f\u5834\u5408\u306f\u3001\u75c7\u72b6\u304c\u3044\u3064\u59cb\u307e\u308a\u3001\u4e2d\u65ad\u5f8c\u306b\u3069\u3046\u5909\u308f\u3063\u305f\u304b\u3082\u4f1d\u3048\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>\u85ac\u306e\u52b9\u679c\u304c\u6b8b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u4e2d\u6b62\u3057\u305f\u65e5\u304b\u3089\u75c7\u72b6\u3078\u306e\u6ce8\u610f\u304c\u4e0d\u8981\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d6\u30fb8.3\u9805<\/a>\u3002<\/small><\/p>\n<p><a href=\"https:\/\/aclinic.jp\/column\/manjaro-olshinryo-nashi\/\">\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u8a3a\u7642\u306f\u8a3a\u5bdf\u306a\u3057\u3067\u8cb7\u3048\u308b\uff1f\u8cfc\u5165\u3067\u304d\u306a\u3044\u7406\u7531\u30fb\u4f55\u3092\u805e\u304b\u308c\u308b\u304b\u30fb\u500b\u4eba\u8f38\u5165\u306e\u30ea\u30b9\u30af\u3082\u5fb9\u5e95\u89e3\u8aac<\/a><\/p>\n<h2 id=\"sec07\">\u30de\u30f3\u30b8\u30e3\u30ed\u304c\u3044\u3064\u304b\u3089\u75e9\u305b\u308b\u304b\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<p>\u52b9\u679c\u304c\u51fa\u308b\u6642\u671f\u3084\u6e1b\u91cf\u5e45\u3001\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u5834\u5408\u306e\u5bfe\u5fdc\u306b\u3064\u3044\u3066\u3001\u3088\u304f\u3042\u308b\u8cea\u554f\u306b\u7b54\u3048\u307e\u3059\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">\u30de\u30f3\u30b8\u30e3\u30ed\u304c\u3044\u3064\u304b\u3089\u75e9\u305b\u308b\u304b\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li><a href=\"#sec07-01\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u65e5\u76ee\u304b\u3089\u75e9\u305b\u308b\uff1f<\/a><\/li>\n<li><a href=\"#sec07-02\">\u30de\u30f3\u30b8\u30e3\u30ed\u30671\u30f6\u6708\u306b\u4f55\u30ad\u30ed\u75e9\u305b\u308b\uff1f<\/a><\/li>\n<li><a href=\"#sec07-03\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u306a\u3044\u3068\u304d\u306f\u3069\u3046\u3059\u308b\uff1f<\/a><\/li>\n<\/ul>\n<\/div>\n<\/div>\n<h3 id=\"sec07-01\">\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f55\u65e5\u76ee\u304b\u3089\u75e9\u305b\u308b\uff1f<\/h3>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u59cb\u3081\u308b\u65e5\u3092\u300c\u6295\u4e0e\u4f55\u65e5\u76ee\u300d\u3068\u7279\u5b9a\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/span><\/strong><\/p>\n<p>\u98df\u6b32\u306e\u5909\u5316\u3092\u81ea\u899a\u3059\u308b\u6642\u671f\u3068\u3001\u4f53\u91cd\u304c\u6e1b\u308b\u6642\u671f\u306f\u4e00\u81f4\u3059\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002<\/p>\n<div class=\"ac-attention\">\n<div class=\"ac-attention__head\">\n<div class=\"ac-attention__icon\" aria-hidden=\"true\"><\/div>\n<p><span class=\"ac-attention__title\">\u300c\u6295\u4e0e3\u9031\u300d\u306f\u52b9\u679c\u304c\u51fa\u59cb\u3081\u308b\u65e5\u3067\u306f\u306a\u3044<\/span><\/p>\n<\/div>\n<div class=\"ac-attention__body\">\u98df\u6b32\u3092\u8abf\u3079\u305f\u7814\u7a76\u306e\u300c\u6295\u4e0e3\u9031\u300d\u306f\u3001\u5909\u5316\u3092\u8abf\u3079\u305f\u6642\u70b9\u3067\u3042\u308a\u3001\u5168\u54e1\u306b\u52b9\u679c\u304c\u51fa\u59cb\u3081\u308b\u65e5\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/div>\n<\/div>\n<p>\u958b\u59cb1\u9031\u9593\u306e\u4f53\u91cd\u3060\u3051\u3067\u5224\u65ad\u305b\u305a\u3001\u6295\u4e0e\u65e5\u3068\u4f53\u91cd\u306e\u7d4c\u904e\u3092\u8a18\u9332\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41591-025-03774-9\">Nature Medicine\uff1a\u6295\u4e0e3\u9031\u6642\u70b9\u306e\u98df\u884c\u52d5\u8a55\u4fa1<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec07-02\">\u30de\u30f3\u30b8\u30e3\u30ed\u30671\u30f6\u6708\u306b\u4f55\u30ad\u30ed\u75e9\u305b\u308b\uff1f<\/h3>\n<p><strong><span class=\"marker\">\u30de\u30f3\u30b8\u30e3\u30ed\u306e1\u30f6\u6708\u306e\u6e1b\u91cf\u5e45\u306f\u3001\u958b\u59cb\u4f53\u91cd\u30fb\u7528\u91cf\u30fb\u4f7f\u7528\u671f\u9593\u3067\u7570\u306a\u308a\u307e\u3059\u3002<\/span><\/strong><\/p>\n<p>72\u9031\u306e\u5e73\u5747\u6e1b\u91cf\u7387\u304b\u3089\u30011\u30f6\u6708\u3067\u4f55kg\u75e9\u305b\u308b\u304b\u306f\u8a08\u7b97\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<p>\u8a3a\u5bdf\u3067\u306f\u3001\u3069\u306e\u6642\u70b9\u304b\u3089\u306e1\u30f6\u6708\u306a\u306e\u304b\u3092\u533a\u5225\u3057\u3066\u4f1d\u3048\u307e\u3057\u3087\u3046\u3002<\/p>\n<div class=\"ac-box\">\n<div class=\"ac-box__title\">1\u30f6\u6708\u306e\u4f53\u91cd\u5909\u5316\u3092\u76f8\u8ac7\u3059\u308b\u3068\u304d\u306e\u8a18\u9332<\/div>\n<div class=\"ac-box__body\">\n<ul class=\"ac-list\">\n<li>\u6295\u4e0e\u3092\u59cb\u3081\u305f\u65e5\u3068\u30015mg\u306a\u3069\u306b\u5897\u91cf\u3057\u305f\u65e5<\/li>\n<li>\u5404\u7528\u91cf\u3092\u4f7f\u3063\u305f\u671f\u9593\u3068\u6295\u4e0e\u56de\u6570<\/li>\n<li>\u6bd4\u8f03\u3059\u308b\u671f\u9593\u306e\u958b\u59cb\u6642\u3068\u73fe\u5728\u306e\u4f53\u91cd<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2206038\">SURMOUNT-1\u539f\u8457\uff1a\u6295\u4e0e\u65b9\u6cd5\u30fb\u8a55\u4fa1\u671f\u9593<\/a>\u3002<\/small><\/p>\n<h3 id=\"sec07-03\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u306a\u3044\u3068\u304d\u306f\u3069\u3046\u3059\u308b\uff1f<\/h3>\n<p><strong><span class=\"marker\">\u4f53\u91cd\u8a18\u9332\u3068\u6295\u4e0e\u5c65\u6b74\u3092\u6301\u3063\u3066\u3001\u51e6\u65b9\u533b\u306b\u6cbb\u7642\u306e\u898b\u76f4\u3057\u3092\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p>\u8a3a\u5bdf\u3067\u306f\u3001\u4f53\u91cd\u3060\u3051\u3067\u306a\u304f\u98df\u6b32\u3084\u751f\u6d3b\u3001\u4f53\u8abf\u306e\u5909\u5316\u3082\u4f1d\u3048\u308b\u3068\u3001\u6cbb\u7642\u3092\u898b\u76f4\u3059\u5224\u65ad\u6750\u6599\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<table class=\"ac-table\" style=\"font-size: 11px;\">\n<thead>\n<tr>\n<th>\u8a3a\u5bdf\u3067\u4f1d\u3048\u308b\u9805\u76ee<\/th>\n<th>\u8a18\u9332\u306e\u4f8b<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<th>\u4f53\u91cd\u3068\u6295\u4e0e<\/th>\n<td>\u4f53\u91cd\u304c\u505c\u6ede\u3057\u59cb\u3081\u305f\u6642\u671f\u30fb\u7528\u91cf\u30fb\u6295\u4e0e\u65e5<\/td>\n<\/tr>\n<tr>\n<th>\u98df\u6b32\u3068\u751f\u6d3b<\/th>\n<td>\u98df\u4e8b\u91cf\u30fb\u9593\u98df\u30fb\u6b69\u304f\u6642\u9593\u306e\u5909\u5316<\/td>\n<\/tr>\n<tr>\n<th>\u4f53\u8abf<\/th>\n<td>\u5410\u304d\u6c17\u30fb\u5614\u5410\u30fb\u4e0b\u75e2\u306e\u6709\u7121\u3001\u98df\u4e8b\u3084\u6c34\u5206\u3092\u53d6\u308c\u3066\u3044\u308b\u304b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u4f53\u91cd\u304c\u6e1b\u3089\u306a\u3044\u5834\u5408\u3082\u3001\u81ea\u5df1\u5224\u65ad\u3067\u5897\u91cf\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u5614\u5410\u3084\u4e0b\u75e2\u304c\u7d9a\u304f\u5834\u5408\u306f\u3001\u65e9\u3081\u306b\u51e6\u65b9\u533b\u3078\u9023\u7d61\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><strong><span style=\"color: #ff0000;\">\u6301\u7d9a\u7684\u306a\u6fc0\u3057\u3044\u8179\u75db\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u4f7f\u7528\u3092\u4e2d\u6b62\u3057\u3066\u901f\u3084\u304b\u306b\u53d7\u8a3a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/span><\/strong><\/p>\n<p><small>\u51fa\u5178\uff1a<a href=\"https:\/\/www.pmda.go.jp\/PmdaSearch\/iyakuDetail\/530471_2499422G1024_1_11\">PMDA\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u96fb\u5b50\u6dfb\u6587\u300d7\u30fb8\u30fb11\u9805<\/a>\u3002<\/small><\/p>\n<h2 id=\"sec08\">\u30de\u30f3\u30b8\u30e3\u30ed\u3067\u75e9\u305b\u308b\u6642\u671f\u3084\u4f53\u91cd\u5909\u5316\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308b<\/h2>\n<p><strong><span 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